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Tafenoquine Succinate

CAS No. 106635-81-8

Tafenoquine Succinate( WR 238605 (Succinate) )

Catalog No. M26474 CAS No. 106635-81-8

Tafenoquine Succinate is an 8-aminoquinoline. and is an agent of anti-malarial prophylactic.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Tafenoquine Succinate
  • Note
    Research use only, not for human use.
  • Brief Description
    Tafenoquine Succinate is an 8-aminoquinoline. and is an agent of anti-malarial prophylactic.
  • Description
    Tafenoquine Succinate is an 8-aminoquinoline. and is an agent of anti-malarial prophylactic.(In Vivo):When tested at two times its ED100 (6 mg/kg), Tafenoquine anti-malarial activity is partially restored in humanized/CYP 2D6 knock-in mice .
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    WR 238605 (Succinate)
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    microtubule
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    106635-81-8
  • Formula Weight
    581.589
  • Molecular Formula
    C28H34F3N3O7
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 125 mg/mL (214.93 mM)
  • SMILES
    OC(=O)CCC(O)=O.COc1cc(C)c2c(Oc3cccc(c3)C(F)(F)F)c(OC)cc(NC(C)CCCN)c2n1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Choi BH, Chattopadhaya S, Thanh le N, Feng L, Nguyen QT, Lim CB, Harikishore A, Nanga RP, Bharatham N, Zhao Y, Liu X, Yoon HS. Suprafenacine, an indazole-hydrazide agent, targets cancer cells through microtubule destabilization. PLoS One. 2014 Oct 29;9(10):e110955.
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